DENVER (AP) — San Francisco 49ers center Daniel Kilgore has been carted off the field with a left leg and ankle injury. He will not return.

Kilgore was hurt on Frank Gore’s run up the middle with 9:23 left in the third quarter. He was tended to by trainers before being helped onto a motorized cart and taken off the field.

Kilgore is in his fifth year out of Appalachian State.

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