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Liberia: Doctor given experimental Ebola drug dies

JONATHAN PAYE-LAYLEH
Associated Press

MONROVIA, Liberia (AP) — A Liberian doctor who received one of the last known doses of an experimental Ebola drug has died, officials said Monday. Separately, Canada said it has yet to send out an untested vaccine that the government is donating.

Ebola has left more than 1,400 people dead across West Africa, underscoring the urgency for developing potential ways to stop and treat the disease. However, health experts warn these drugs and vaccines have not undergone the rigorous testing that usually takes place before they are used.

The experimental vaccines are at still at a Canadian laboratory, said Patrick Gaebel, spokesman for the Public Health Agency of Canada, who declined to speculate how many weeks it could be before those are given to volunteers.

“We are now working with the (World Health Organization) to address complex regulatory, logistical and ethical issues so that the vaccine can be safely and ethically deployed as rapidly as possible,” Gaebel said.

Earlier this month, Canada said it would donate 800 to 1,000 doses of an Ebola vaccine that it developed. Likely candidates include health care workers treating Ebola patients.

The experimental drug known as ZMapp has been tried in only six people. Health experts caution that since ZMapp was never tested in humans, it is unclear whether it works. The small supply is now said to be exhausted and it is expected to be months before more can be produced.

Dr. Abraham Borbor, the deputy chief medical doctor at Liberia’s largest hospital, had received ZMapp, along with two other Liberians. He “was showing signs of improvement but yesterday he took a turn for the worse,” and died Sunday, Information Minister Lewis Brown told The Associated Press.

There was no update provided Monday on the other two Liberians who received the drug.

Earlier, it had been given to two Americans aid workers and a Spanish missionary priest, who died after he left Liberia. After receiving rigorous medical care in the U.S., the Americans survived the virus that has killed about half of its victims.

Ebola can cause a grisly death with bleeding from the eyes, mouth and ears. The virus can only be transmitted through direct contact with the bodily fluids of the sick or from touching victims’ bodies, leaving doctors and other health care workers most vulnerable to contracting it.

International relief efforts have included shipments of gloves, gowns, face masks and other protective equipment, although it’s not clear how many have reached health workers struggling to contain the epidemic in West Africa, where even such basics as sterile fluids can be in short supply.

But just getting enough gear isn’t the whole story: Health workers can infect themselves while taking off contaminated equipment if they don’t do it properly, a trio of infectious disease experts wrote Monday in Annals of Internal Medicine.

“The physical exhaustion and emotional fatigue that come with caring for patients infected with Ebola may further increase the chance of an inadvertent exposure to bodily fluids on the outside of the” personal protective equipment, wrote Dr. William A. Fisher II of the University of North Carolina, Chapel Hill, along with Drs. Trish Perl and Noreen Hynes of Johns Hopkins University.

“In addition, the impulse to wipe away sweat in the ever-present hot, humid environment” after taking off some gear, and before washing up, could be enough, they added.

Meanwhile, the family of 29-year-old William Pooley, the first British citizen confirmed to be infected with Ebola, said he is receiving excellent care at an isolation ward in London’s Royal Free Hospital after being evacuated from the capital of Sierra Leone.

“We could not ask for him to be in a better place,” they said in a statement.

Pooley, a volunteer nurse, was flown back to Britain from Sierra Leone where he was working at an Ebola treatment center.

The WHO is also in the process of trying to evacuate a Senegalese doctor who contracted Ebola while working in Sierra Leone, said WHO Assistant Director General, Dr. Keiji Fukada on Monday.

The U.N. on Monday also spoke out against the limitations placed on flights into and out of the affected countries, saying they are slowing aid organizations’ work in sending personnel and equipment and contributing to the countries’ “economic and diplomatic isolation.”

“We shouldn’t do anything that stokes fear and stigmatization,” Stephane Dujarric, spokesman for the U.N. secretary-general, told reporters.

On Monday, Japan also said it is ready to provide a newly developed anti-influenza drug as a possible treatment Ebola. The drug, with the brand name Avigan, was developed by Fujifilm subsidiary Toyama Chemical Co. to treat new and re-emerging influenza viruses, and has not been proven to be effective against Ebola.

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Gillies reported from Toronto. Associated Press writers Lauran Neergaard in Washington, Cara Anna at the United Nations, Mari Yamaguchi in Tokyo, and Clarence Roy-Macaulay in Freetown, Sierra Leone contributed to this report.

Copyright 2014 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Don’t Settle for Student Loans to Pay for Online Education

Online college programs are becoming a more popular choice for prospective students, with one study finding that more than 6 million students enrolled in at least one online course in fall 2015. The popularity of these courses can be attributed in part to their flexibility with working adults' schedules, students' ability to progress more quickly through online programs and, oftentimes, cheaper tuition. [See 10 low-cost online bachelor's programs for out-of-state students.]Online degrees can be beneficial to many college students, but some studies have shown online learners complete their programs at lower rates than students at traditional brick-and-mortar campuses. Individuals with student loans but no degree comprise two-thirds of defaulted borrowers. Though these numbers are not encouraging, just like for traditional programs, there are ways to reduce how much you'll need to borrow for an online program to ensure you won't become one of these statistics. Don't just settle on borrowing student loans to cover the whole cost of your program and living expenses. Instead, start thinking about how to cut costs and cover your balance in different ways, such as the following. -- Grants and scholarships: Even though you are taking an online course, you can still apply and receive grants and scholarships. But your first step should be to complete the Free Application for Federal Student Aid, commonly referred to as the FAFSA, which will allow you to receive a Pell Grant if your expected family contribution is low enough. The EFC criteria and award amounts are adjusted annually, but the 2017-2018 academic year awards range from $606 to $5,920, which could significantly lower the amount you borrow annually. Your next step is to apply for scholarships. You can start by checking online scholarship search engines, such as the Salt Scholarship Search, College Board's BigFuture and Peterson's. But don't forget to take advantage of local organizations and your school's financial aid office. Both may offer scholarships that you can't find with a national scholarship search. [Review these 10 sites to kick off your scholarship search.]For instance, organizations like the Elks Club, Knights of Columbus or the Rotary Club typically offer scholarships annually to local students. Just because you're going to school online doesn't mean you're ineligible. Visit your local library for scholarship listings, and ask around town. You might be surprised how many local organizations offer scholarships. While these scholarships typically aren't large, every little bit counts. Each dollar you receive in a scholarship is a dollar you don't have to borrow and pay interest on. -- Work-study: Another option for online students may be work-study awards. Not all students enrolled in online programs are eligible, but students at some schools -- including, for example, SUNY Empire State College and Liberty University -- are. Work-study awards are not given upfront like scholarships and grants. In most cases, they are an offer to earn up to the awarded amount if you secure an eligible work-study job. While there is a misconception that all work-study jobs must be on campus, students can work for off-campus, nonprofit or public employers as long as the work is in the public's interest. You may be able to work for a for-profit employer if the job is relevant to your course of study. No matter who the outside employer is, it will need to have an established agreement with your college for you to receive work-study funds. Remember, to be eligible for federal financial aid, you must be enrolled and pursuing a degree or certificate. If you're not working toward a credential, Pell Grants and work-study won't be option, but you may still be able to take advantage of private scholarships -- just be sure to read the eligibility criteria carefully. [Explore what to know about financial aid in online programs.]-- Pay as you go: One of the great benefits to enrolling online is the flexible schedule, which can allow you to complete your college coursework around your responsibilities. But prospective students often overlook using their part- or full-time job earnings as an option for paying for college. Almost 80 percent of college students in 2015 worked at least part time while attending classes, according to the National Center for Education Statistics. By budgeting and thinking strategically about your college costs, you can likely reduce your dependence on student loans by paying a portion out of pocket. Many -- but not all -- online programs are less expensive than traditional programs and often have shorter payment periods. Six, eight or 10 weeks are common course durations. Because of the frequency of payments in an online setting, you may be well-placed to pay as you go and possibly avoid borrowing altogether. Attending college online and avoiding student loans may be challenging, but if you are willing to put in the effort, you can limit the amount you need to borrow. More from U.S. News Q&A: Understanding Student Loan Discharge Eligibility Student Loan Refinancing Isn't Right for All Borrowers
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