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NIH scientists work on universal flu vaccine

Paula Wolfson, wtop.com

BETHESDA, Md. – It could be a huge game changer in flu prevention.

Scientists are developing a universal vaccine that will offer protection against any and all flu strains, and the nucleus of that research is in the D.C. region.

It’s taking place at the Vaccine Research Center at the National Institutes of Health, which was originally established in the mid-1990s to develop an AIDS vaccine.

That work is continuing, but the mission of the center is broader and these days, work on a universal flu vaccine is another big priority.

Dr. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases, convinced former President Bill Clinton to launch the center at the height of the AIDS epidemic.

“This is one of the few places anywhere where you can really have a ‘soup to nuts’ approach, where in the same building, the same camaraderie, you go from very basic research up through and including manufacturing a pilot lot of vaccine…to an actual clinical trial,” he says,

It’s an approach well suited to the challenge of creating a breakthrough in flu prevention. Current vaccines target a part of the virus that changes or “drifts” over time. That is why there is a new vaccine every year.

Scientists have found a part of the virus common to all flu strains but, for some reason, the immune system cannot see it.

Using molecular engineering and other high-tech tools, scientists at the Vaccine Research Center are looking for a way to get the body to create an immune response to that hidden virus “stem.”

Watch an animation of the flu virus:

Dr. Rick Koup, director of the immunology lab, says there’s a sense of optimism among the 100 or so staffers at the center.

“We know that we can induce the types of antibodies that have universal targeting of the different strains of influenza,” he says.

Koup says translating this into an actual product that can be manufactured may take a few years, maybe longer. But a tour of the lab reveals excitement, and Koup says everyone knows what is at stake.

“If we had a universal vaccine where basically you get the vaccine and you are protected against virtually all of the strains that are out there, it would be a huge game changer.”

A universal vaccine would remove the annual uncertainty over which strains are likely to strike and when. It would also take away the inconvenience of getting a flu shot every year, and Fauci predicts that will encourage more people to get vaccinated.

But don’t ask him for a timetable. Fauci says 10 years ago he wasn’t even sure a universal vaccine was possible. But now, though he can’t say when, he believes it will happen

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(Copyright 2013 by WTOP. All Rights Reserved.)

Don’t Settle for Student Loans to Pay for Online Education

Online college programs are becoming a more popular choice for prospective students, with one study finding that more than 6 million students enrolled in at least one online course in fall 2015. The popularity of these courses can be attributed in part to their flexibility with working adults' schedules, students' ability to progress more quickly through online programs and, oftentimes, cheaper tuition. [See 10 low-cost online bachelor's programs for out-of-state students.]Online degrees can be beneficial to many college students, but some studies have shown online learners complete their programs at lower rates than students at traditional brick-and-mortar campuses. Individuals with student loans but no degree comprise two-thirds of defaulted borrowers. Though these numbers are not encouraging, just like for traditional programs, there are ways to reduce how much you'll need to borrow for an online program to ensure you won't become one of these statistics. 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If you're not working toward a credential, Pell Grants and work-study won't be option, but you may still be able to take advantage of private scholarships -- just be sure to read the eligibility criteria carefully. [Explore what to know about financial aid in online programs.]-- Pay as you go: One of the great benefits to enrolling online is the flexible schedule, which can allow you to complete your college coursework around your responsibilities. But prospective students often overlook using their part- or full-time job earnings as an option for paying for college. Almost 80 percent of college students in 2015 worked at least part time while attending classes, according to the National Center for Education Statistics. By budgeting and thinking strategically about your college costs, you can likely reduce your dependence on student loans by paying a portion out of pocket. 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